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Arthritis Health Center

Calcium Pyrophosphate Dihydrate Crystals Directory

Calcium pyrophosphate dihydrate crystals (CPPD) that form in one or more joint cartilages may be a sign of a rare, inherited metabolic disorder called familial articular chondrocalcinosis. The crystals eventually cause damage to the joints, often the knees. Symptoms of familial articular chondrocalcinosis mimic those of classical gout and may include swelling, stiffness, and pain, usually in one joint. Chondrocalcinosis occurs in hereditary and sporadic forms. Treatment includes anti-inflammatory medication. Follow the links below to find WebMD's comprehensive coverage of calcium pyrophosphate dihydrate crystals, how they form, what they mean, and much more.