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Polymyalgia Rheumatica and Giant Cell Arteritis - Treatment Overview

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Your doctor gradually lowers the amount of medicine you take. How quickly he or she does this varies with the individual.

  • In polymyalgia rheumatica, most people have to take corticosteroids for about 2 years.
  • In giant cell arteritis, most people have to take corticosteroids for 1 to 2 years, although many people with the condition need them for longer than 2 years.

If your symptoms do not improve with corticosteroid medicine, your doctor may need to test you for other conditions that are similar to polymyalgia rheumatica or giant cell arteritis.

Your doctor will track your condition while you are taking corticosteroid medicine and for 6 to 12 months after you stop taking the medicine. This tracking may include regular appointments or telephone calls to discuss your symptoms and tests to measure your erythrocyte sedimentation rate (ESR) or your C-reactive protein (CRP) value.

See a table comparing corticosteroid treatment of polymyalgia rheumatica and giant cell arteritis.

If you need long-term corticosteroid treatment for either condition, you are at risk for bone thinning (osteoporosis). This is because corticosteroids decrease how well your body takes in calcium, which is important in building strong bones. Your doctor may recommend a bone density (DEXA) test to see if you need medicine (bisphosphonates) to prevent osteoporosis. Or he or she may simply start you on bisphosphonates without the test. For more information, see the topic Osteoporosis.

Treatment if the conditions get worse

In both polymyalgia rheumatica (PMR) and giant cell arteritis (GCA), your symptoms may return (relapse) after a period of improvement. This often occurs in the first 2 years of treatment or during the first 12 months after you stop taking corticosteroid medicine. A relapse usually occurs if the dose of corticosteroids is reduced or withdrawn too quickly. But up to 50% of people with either condition have a relapse over the first 2 years that is not related to how corticosteroids are used.2 If you have a relapse of symptoms, your doctor will increase the corticosteroid dosage for a period of time, then gradually decrease it after your symptoms are gone.

See a table comparing corticosteroid treatment of polymyalgia rheumatica and giant cell arteritis.

In rare cases, giant cell arteritis can affect the main part of the aorta in the chest, rather than one of its smaller branches, causing an aortic aneurysm. If this were to happen, you would feel severe chest pain that could extend to your back, and you could faint or have symptoms of a stroke. If you have giant cell arteritis and have such symptoms, contact your doctor or call911immediately. Though rare, such an event may be life-threatening. Your doctor may recommend that you have an annual chest X-ray to watch for an aortic aneurysm.

WebMD Medical Reference from Healthwise

Last Updated: April 13, 2011
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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