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Reviewed By: Laura Martin,
SOURCES: 2008 Medical Reference from Medstar Television. Laura Hummers, MD, Rheumatologist, Johns Hopkins Bayview Medical Center, Baltimore.
© 1999-2011 Medstar Television
When the temperature drops, Angela Lewis picks up her gloves. She has Raynaud's phenomenon and needs to keep her fingers warm.
Or even if I have gloves on, some days it's just so cold and they're so sensitive that the gloves don't help right away.
In Raynaud's, the blood vessels constrict and spasm in cold weather. The fingertips turn white, blue or red with tingling, numbness and extreme pain.
I tell patients that that's like a heart attack of the skin. I mean, their tissue at the tip of their finger is not getting enough blood flow and it hurts like that.
Now the same drug that stops chest pain by widening blood vessels to the heart, may provide relief to Raynaud's patients.
This would be the first drug that was specifically studied and sent to the FDA for the treatment of Raynaud's Phenomenon.
Johns Hopkins researchers are testing a nitroglycerin gel.
The problem with nitroglycerin formulations as they stand right now is that they come with a significant amount of side effects. So you put the medication on your skin and it absorbs into your whole body.
However the new gel is only absorbed where it's applied. And the results of the study are promising.
They all suggested that there was an improvement in blood flow and that there was improvement in the Raynaud's severity in people who were on treatment compared to placebo.
I don't know if I had gel or placebo. But I'm pretty sure that, at one time, I did have gel, because I put it on and it warms the hands up. And it warms them up kinda quick!
Now Angela's crossing her fingers that the gel will soon be on the market. For WebMD, I'm Damon Meharg.
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